About this matrix
This matrix shows p-values and beta estimates from Cox-proportional hazard models using plasma metabolite levels as the exposure and the risk of 27 diseases (ICD-10 codes) and all-cause mortality (sex-adjusted as well as stratified by sex; >20 years of follow-up).
You can filter/subset the matrix based on statistical criteria, such as association strength or effect estimates, or restricted to an exposure or outcome of interest using the "Settings" menu.
Plot legend
Rows |
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Metabolite name and superpathway (abbrv.) |
Columns |
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Trait name and group (abbrv.) |
Cells |
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Association between metabolite and traits.
Number: ⌊-log10(p)⌋.
Color: effect size and direction, ranging from -1 (blue) to +1 (red). |